PRP Shoulder Injections in San Jose

Dr. Pamela Mehta MD
Orthopedic Surgeon in San Jose

PRP Injections for your shoulder

Dr. Pamela Mehta is an experienced orthopedic surgeon renowned for her expertise in sports injuries and regenerative medicine. She is the founder of Resilience Orthopedics.

With an impressive career and training under leading innovators, she has served as Chief of Orthopedics and National Orthopedic Director for a major orthopedic hospitalist group and advises several publicly traded companies.

Pamela Mehta

If you’re dealing with shoulder pain that hasn’t improved with rest or standard care, PRP injections may help. This treatment uses your blood to support healing of your injured shoulder tissue.

I may recommend it for conditions like rotator cuff tears, tendinitis, or impingement.

Some of my patients have noticed less pain and better movement over time, though results may vary. It’s a safe option that may support long-term healing instead of quick relief.

In this article, I’ll explain how PRP works for shoulder pain, what to expect, and whether it could be a good fit for you.

Key Takeaways

  • PRP uses your own blood to help your shoulder heal.
  • It may help with frozen shoulder, tendinopathy, and partial tears.
  • After PRP, you may experience improvement in 4–6 weeks, with results lasting 6–12 months or longer.
  • Unlike steroid shots, PRP supports healing instead of just reducing pain.
  • Staying active with gentle rehab helps you get the most from the treatment

How Does PRP Work?

When you’re dealing with a shoulder injury, the healing process may be slow, especially in areas with poor blood flow. That’s where PRP can help.

We use a small sample of your blood and concentrate the part rich in platelets. These platelets have growth factors that support healing.  

The concentrated plasma is then injected into the injured part of your shoulder (a tendon, joint, or surrounding tissue).

Once it’s there, the platelets release signals that may:

  • Reduce inflammation
  • Improve circulation
  • Stimulate tissue repair

This leads to improved shoulder movement, less pain when reaching overhead, and better sleep.

Who Is it For and Who Should Avoid It?

Not everyone with shoulder pain is a good candidate for PRP. Its suitability depends on the kind of injury you have, how severe it is, and your overall health.

I may recommend shoulder PRP if your pain hasn’t improved with rest, physical therapy, or anti-inflammatory medications.

PRP may be helpful for shoulder conditions such as:

  • Rotator cuff tendinopathy
  • Partial tears
  • Bursitis
  • Shoulder impingement
  • Frozen shoulder
  • Joint inflammation 

These are usually conditions where surgery isn’t needed right away, or you might prefer to avoid surgery if possible.

If you’re active or play sports, PRP might help you recover faster and get back to the things you love. But it’s not a fix-all option. 

For example, if your tendon is completely torn and needs surgical repair, PRP alone won’t be enough.

Book a Consultation with Dr. Pamela Mehta, MD

The Best Orthopedic Surgeon in San Jose

Dr. Mehta is a board-certified orthopedic surgeon who can help you recover from your joint condition. If you:

  • Are Suffering From Pain and Mobility Issues
  • Need Orthopedic Assessment and Advice
  • Want Treatment From a Top Orthopedic Doctor

We Can Help

There are also times when I don’t recommend PRP, as it may not be safe:

  • Uncontrolled diabetes
  • Active infections 
  • Bleeding disorders 
  • Certain autoimmune conditions

It’s also not advised during pregnancy or while breastfeeding. That’s why I always start with a careful medical assessment before recommending it.

doctor with a vial of prp plasma

PRP vs Steroid Injections for Shoulder Pain

I often get asked whether steroid injections or PRP is the better option for shoulder pain. The answer depends on your goals.

Steroid injections offer faster, short-term relief by reducing inflammation. PRP works differently. It takes longer to feel the effects, sometimes a few weeks. But it focuses on healing the injured tissue itself.

Here’s a quick comparison to give you a better idea:

FeaturePRP InjectionsSteroid Injections
Main ActionUses your own platelets to support tissue repair in areas like the rotator cuffReduces inflammation in the joint or surrounding tissues
Onset of ReliefSlower (days to weeks)Fast (often within 1–2 days)
Duration of EffectLong-term improvement (months)Short-term relief (weeks to a few months)
Cause of Pain AddressedYes – targets the sourceNo – mainly manages symptoms
Repeat Use and Side EffectsSafe to repeat, as it’s from your own bloodLimited as repeated use may weaken tendons or cartilage over time

Shoulder Conditions Treated By PRP

1. Rotator Cuff Tears

PRP may reduce pain and support the healing of the damaged tissue for partial rotator cuff tears or chronic inflammation.

It won’t repair a full tear that needs surgery. But it may improve strength and movement for smaller tears. (Especially when lifting your arm or sleeping on that side has become difficult.)

2. Frozen Shoulder

If your shoulder feels stiff and painful to move, you might be dealing with a frozen shoulder. 

In such cases, PRP injections may reduce inflammation and make physical therapy more effective.

While it won’t resolve the issue overnight, it may help speed up a slow recovery process.

3. Shoulder Tendinopathy

Chronic tendon pain around the rotator cuff or biceps is common in people with repetitive overhead activity. 

When therapy hasn’t helped, PRP may support tissue repair and reduce the ongoing irritation that makes motion painful.

4. Shoulder Osteoarthritis

During the early to mid stages of shoulder arthritis, PRP may ease pain and stiffness. While it can’t restore cartilage, it reduces inflammation and improves shoulder movement.

For some people, this may delay the need for surgery and make day-to-day activities more manageable.

doctor injecting platelet-rich plasma into patients shoulder

The Procedure

The process itself is simple and usually takes about 30 minutes. Here’s what you can expect: 

1. Consultation

I’ll begin by examining your shoulder and reviewing your medical history. After that I’ll confirm if PRP is the right fit for your condition.

2. PRP Preparation

A small blood sample (about two tablespoons) is taken and spun in a centrifuge to separate the platelets that help with healing.

3. Injection Process

Once the PRP is ready, it’s injected into the injured part of your shoulder. Ultrasound guidance is used to make sure that it goes exactly where it’s needed.

4. Post-PRP Care

Your shoulder joint might feel a bit sore or stiff after the injection, and that’s completely normal. Rest the shoulder for a few days and avoid heavy lifting or workouts for about a week.

doctor performing prp injection into patients shoulder

How Painful Is Shoulder PRP?

It’s common to feel nervous about a shot directly into the shoulder, especially when it’s already sore. But most of my patients are surprised by how quick and manageable it is.

Before the injection, I numb the skin and the deeper shoulder tissue, so you’ll mostly feel pressure or a brief pinch. The injection itself takes just a few seconds.

Over the next 24 to 72 hours, it’s normal for your shoulder to feel achy or sore.  Some of my patients tell me it feels like they overdid it during a shoulder workout. 

Here’s what you can expect after that:

  • Sleeping may be a little uncomfortable if you’re used to lying on that side. I usually suggest using extra pillows to stay off the treated shoulder.
  • Ice packs may help with discomfort during the first day or two. 
  • I also ask patients to avoid anti-inflammatory medications like ibuprofen or naproxen. 

These can interfere with the healing effects of PRP. If needed, acetaminophen is usually okay.

While this soreness is expected, it goes away quickly. Knowing what to expect and how to manage it can make things easier.

Illustration showing the progression of pain in shoulder PRP.

Benefits

  • PRP injections supports repair in areas like the rotator cuff, which often don’t heal well on their own.
  • It’s an in-office procedure with no stitches and little downtime.
  • May reduce inflammation and pain, which makes movement easier.
  • A good option when conservative care hasn’t worked.
  • May Improve mobility and comfort, which leads to better shoulder function over time.

Risk and Side Effects

PRP injections in the shoulder are generally well-tolerated. Most of my patients do just fine after the procedure.

Here’s what you might experience after your PRP injection:

  • Mild soreness or swelling around the shoulder joint
  • Stiffness or tightness
  • Bruising at the injection site
  • Rare chances of Infection (rare)

Note: Some people don’t notice much improvement with PRP.

If you experience unusual pain or fever or your shoulder feels worse instead of better, reach out. It’s always better to check in early.

PRP might not be right for you if you have medical conditions like cancer, a serious infection, or a low platelet count. That’s why I review your full medical history before recommending anything.

Shoulder PRP injection Recovery Timeline

How Long Does It Take To Work?

The first six weeks after a PRP injection are when you may notice your shoulder responding to treatment.

Week 1:

  • Expect some soreness and stiffness around the shoulder joint. 
  • Swelling is normal, especially if the injection was near the rotator cuff or bursa. 

I usually suggest that patients avoid lifting, overhead movement, or sleeping on that side. Ice and rest may help with discomfort.

Week 2:

  • Inflammation and soreness often begin to settle.
  • Many patients tell me daily tasks like getting dressed or reaching across the body feel a little easier.

Week 3–4:

  • By this point, the shoulder often feels more stable.
  • This is when I recommend gentle exercises or physical therapy to restore the range of motion. 

Week 5–6:

  • Shoulder strength and motion begin to improve.
  • Discomfort continues to decrease, and everyday tasks may feel easier to manage.
  • You may return to light physical activity as per the guidance provided.

By the end of week 6, most people feel they’re finally making progress.

How Long Do the Effects Last?

You may start feeling the full benefits of PRP injections by 2 to 3 months. For shoulder injuries, results can last anywhere from 6 to 12 months and sometimes longer.

To benefit from the procedure: 

  • Stick with your physical therapy plan 
  • Avoid activities that strain the joint
  • Sleep in a position that doesn’t put pressure on your shoulder
  • Keep your posture and movement patterns in check

For chronic issues like arthritis, a repeat injection may be needed after 12 to 18 months. PRP isn’t always permanent. But with the right care, it may give long-term relief.

Shoulder Rehabilitation After PRP

PRP injections helps your shoulder heal. But physical therapy keeps that healing on track.

We usually start rehab a few days after the injection once the soreness reduces.

The first step is to get your range of motion back. Shoulder injuries often cause stiffness, especially if you’ve been avoiding movement. Gentle stretches and guided exercises help loosen things up.

Next, we focus on strength. The rotator cuff and shoulder blade muscles keep your joint stable. Building them up protects the shoulder and lowers the risk of re-injury.

We also plan how to return to activity, step by step. That could mean lifting your arm overhead, reaching behind you, or getting back to tennis. We increase the load slowly so your shoulder can handle more without setbacks.

Rehab after PRP injection is just as important as the injection itself. It helps you move better, feel stronger, and stay pain-free longer.

Ready to Recover?

Take the first step in getting back to your normal self, and book an appointment with Dr. Mehta today.

We’re ready when you are!

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Kevin and Harjeet Janda
June 20, 2026
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Dr. Pamela was amazing. She was so thorough and knowledgeable, and when my son got injured, she acted quickly instead of taking a wait-and-see approach. Her team got us in for an X-ray the very same day, which I really appreciated. What stood out most was that she took the time to really understand what happened and what was causing the problem. I never felt rushed during our appointment. She listened, answered all of our questions, and made us feel like we were her only patients. That level of attention and care is hard to find these days. Everyone in the office was professional, kind, and efficient. As soon as the imaging results were ready, Dr. Pamela personally called to go over everything, explain the plan, and discuss the next steps. I would recommend her to anyone looking for orthopedic care. She’s incredibly knowledgeable, genuinely kind, and you can tell she truly cares about her patients and their families. She truly cares from the heart, and it shows.
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Sherri Dodd
May 20, 2026
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So thankful to have been recommended to Dr. Mehta a few years ago! My first experience with her was the meniscus surgery, which she performed perfectly, and I was back to my former fitness level in a short time! What she has helped me with even more are my low back problems, including three bulging discs and stenosis. I’ve had three stem cell injections over the years. (In the middle of these, I tried a different procedure with a different provider, and it was awful!) Had my most recent injection yesterday and the relief was immediate! My son has also been to her for a sports shoulder injury and my husband with his knee. We really appreciate Dr. Mehta, her expertise, and the helpful people she has chosen for her office!
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Andrew Ferguson
April 24, 2026
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Dear Dr. Mehta, Thank you for your wonderful care. Age and injuries often times create a long road back, requiring more patience than I would like. Since your PRP injection — (Platelet-Rich Plasma) I have road a mountain bike, hard. I’ve ridden my peloton, hard. I’ve surfed big waves. I’ve hiked uphill with a weight vest, far. I’ve done yoga, but I had not run… Titled: I ran today. I ran today. Not far, But I ran. Not fast, But I ran. Walk/run intervals, but I ran. Andddddd Pain free 5 minute ice plunge after No Advil needed Cautiously optimistic with spring in my step. So appreciative of your care and advice(even the parts I didn’t want to listen to) Andrew
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John Alviter
April 17, 2026
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Dr. Pamela Mehta was incredible. Her professional advice, support, and injections made a huge difference in my recovery. She took the time to understand exactly what I was dealing with and guided me every step of the way. Because of her care, I am now back to my normal routine, including gym workouts, running, and biking, completely pain free. I am truly grateful for everything she did to help me get back to my normal life. Highly recommend!!!
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Nelly García-Rangel
April 16, 2026
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Dr Mehta is knowledgable, skilled, and dedicated. She is confident in her treatment and i appreciate that she doesn’t resort straight to surgery when there’s a chance your body can heal on its own. She is great!!
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Rikin Ladwa
April 16, 2026
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As an patient with a sharp disability on the same leg as my ACL tear, Dr Mehta not only performed a flawless specialized surgery but also provided my family and I with clarity and confidence in my recovery process. She took the time to explain everything in a way that made sense, answer my questions thoroughly and ensure I'm properly set up with PT that helps Because of her I've been able to make a full recovery in a tough situation, I'm extremely thankful to her and the secs for writing all the notes/prescriptions I needed swiftly .. !!
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amy winford
April 14, 2026
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Dr Mehta was fantastic. She assessed my knee pain, listened to my concerns and scheduled my surgery promptly. The surgery went well and I am postop six weeks and just returned from a four day trip to San Antonio where I did a lot of walking. I feel like my knee is progressing well. She was thorough and has a great bedside manner. I would 10 out of 10 recommend her.
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Danny Valverde
March 19, 2026
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Muy buen servicio
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Bart Giordano
March 14, 2026
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My shoulder injury was mis-diagnosed by another practitioner and I struggled with pain, mobility issues and PT for 6 months. After one visit with Dr. Mehta, 4 weeks later I am pain free and back in action!
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Kathryn Risk
March 14, 2026
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Saw Dr. Mehta for debilitating hip pain. She prescribed PRP and physical therapy, and I am happy to report that I have very little pain now. She was very thorough and patiently answered all my questions. I would recommend her very highly to anyone needing an Orthopedic specialist.

What Regenerative Medicine Services Do We Offer?

Platelet-Rich Plasma (PRP)

PRP injections use the plasma in your own blood to help boost your body's healing capabilities. It is a new an emerging treatment that could help you to avoid a surgical procedure.

Stem Cell Injections

Stem cell injections are a cutting-edge treatment to help provide "fresh" cells to areas where your body cannot heal itself. This is an innovative treatment for orthopedic conditions.

BMAC

BMAC therapy uses your body’s own bone marrow cells to support healing in areas that struggle to recover on their own. It is an innovative, regenerative option commonly used in orthopedic care.

General Information

Learn more about regenerative medicine and orthobiolgics.

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