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Platelet-rich plasma (PRP) is a form of regenerative medicine that helps your body repair itself. Many people turn to it as a gentler option than surgery for knee, shoulder, elbow, and other orthopedic issues.
Although the treatment is minimally invasive, the body still needs a brief period of rest afterward. The recovery is far shorter than what you’d face after an operation.
At Resilience Orthopedics in San Jose, Dr. Pamela Mehta guides patients through the latest evidence-based treatments. She brings years of experience in orthopedic surgery, sports injuries, and regenerative medicine.
Book a Consultation with Dr. Pamela Mehta, MD
The Best Orthopedic Surgeon in San Jose
Dr. Mehta is a board-certified orthopedic surgeon who can help you recover from your joint condition. If you:
- Are Suffering From Pain and Mobility Issues
- Need Orthopedic Assessment and Advice
- Want Treatment From a Top Orthopedic Doctor
We Can Help
What Happens to The Body After PRP?
PRP uses your own blood, which is processed to concentrate the platelets and growth factors. After the injection, these components settle into the joint and help the body begin the repair process, improve blood flow, and support tissue regeneration.
Your body needs time to respond to the injection. Light walking is fine for the first 24 to 72 hours. It helps prevent stiffness without putting stress on the joint. Intense exercise should be avoided, as it can interfere with the repair process.
Dr. Mehta’s approach relies on current evidence and conversations about your goals and concerns. At Resilience Orthopedics, we tailor every plan to you, because healing looks different for everyone.

How Long to Wait to Exercise After PRP Injection
After PRP injection, your body needs time to start healing. Moving too soon can slow recovery, but taking it slow doesn’t mean long downtime.
Here’s a week-by-week guide to help you safely regain strength and mobility:
| TIMEFRAME | GOAL | RECOMMENDED ACTIVITIES |
| Days 1–2 | Immediate rest | Keep weight off the treated area. Use ice if your doctor recommends it. Keep the injection site clean. |
| Days 3–7 | Gentle mobility | Take short walks for 5–10 minutes once or twice a day. Slowly move the joint to keep it flexible. Avoid stretching and resistance band workouts. |
| Week 2 | Light functional movement | Walk up to 20 minutes.Add gentle stretching, light yoga, and simple isometric exercises. |
| Week 3 | Controlled strength work | Start bodyweight exercises and light resistance band workouts. Continue gentle movement. |
| Week 4 | Gradual return to full activity | Try low-impact cardio such as cycling or swimming. Increase resistance slowly. Begin easy sport-specific drills. |
| Week 5-6 | Performance rebuilding | Start moderate-intensity workouts.Add agility, balance, and coordination drills. Return to non-contact practice. |
| Week 6-8+ | Full return to sport/training | Resume full training if pain-free. Add plyometrics and other power-based movements. Watch for any lingering symptoms and adjust as needed. |
After PRP
PRP is generally safe and has few side effects. But after the injection, it’s normal to notice some reactions at the treatment site, such as:
- Mild to moderate pain
- Swelling or redness
- Bruising
- Mild itchiness
- Tingling
Warning Signs and When to Contact Your Doctor
If any of these symptoms get worse after 72 hours, it’s important to contact your doctor right away. Watch for:
- Increasing pain, swelling, or tingling
- Bruising or redness spreading beyond the injection site
- Any discharge from the injection site
- Fever or chills
- Shortness of breath
Ready to Recover?
Take the first step in getting back to your normal self, and book an appointment with Dr. Mehta today.
We’re ready when you are!
FAQs
Can I Drive After PRP Injection?
You should wait 72 hours before driving, as long as you feel comfortable. Driving right after the injection can be risky.
You may still feel numb from the local anesthesia or experience some pain. It’s safer to arrange a ride home.
When Can I Return to Work?
If your job is mostly desk-based, you can go back the next day. Jobs that involve manual labor, standing, or walking for long periods require more recovery time.
Listen to your body and take it easy.
What If I’m Not Progressing Normally?
Dr. Mehta will check your progress at 6 weeks and 3 months. Some improvement can take longer to appear.
But if your progress is slower than expected, she will reassess and discuss further treatment options. If you notice any concerning symptoms, contact Dr. Mehta right away.